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Article

Effects of lasofoxifene on the pharmacokinetics and pharmacodynamics of single-dose warfarin.

British journal of clinical pharmacology - 1 Jun 2006

Ouellet Daniele, Bramson Candace, Carvajal-Gonzalez Santos, Roman Doina, Randinitis Edward, Remmers Ann, Gardner Mark J

Abstract excerpt

AIM: To investigate the effect of steady-state lasofoxifene on the pharmacokinetics and pharmacodynamics of warfarin. METHODS: Twelve healthy postmenopausal women received warfarin (single 20-mg dose) alone and during lasofoxifene. R- and S-warfarin concentrations, prothrombin time (PT) and international normalized ratio (INR) were determined with each treatment. RESULTS: Lasofoxifene had no clinically meaningful...

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Identifiers

PMID: 16722839
DOI: 10.1111/j.1365-2125.2006.02589.x
PMCID: PMC1885106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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