Article
Association of spermatogenic failure with decreased CDC25A expression in infertile men.
Human reproduction (Oxford, England) - 1 Sept 2006
Cheng Yu Sheng, Kuo Pao Lin, Teng Yen Ni, Kuo Ting Yi, Chung Chia Ling, Lin Ying Hung, Liao Rui Wen, Lin Johnny Shinn Nan, Lin Yung Ming
Abstract excerpt
BACKGROUND: DAZ gene family is crucial for human spermatogenesis that requires the precise co-ordination of cell cycle events. CDC25A is recognized as the downstream substrate of DAZ gene family and is thought to function on the M-phase regulation of cell cycles. We investigated the expression profiles of CDC25A in the testes of infertile men and evaluated the relationship between CDC25A levels and testicular...
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