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Article

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

Cell - 19 May 2006

Lim Janghoo, Hao Tong, Shaw Chad, Patel Akash J, Szabó Gábor, Rual Jean-François, Fisk C Joseph, Li Ning, Smolyar Alex, Hill David E, Barabási Albert-László, Vidal Marc, Zoghbi Huda Y

Abstract excerpt

Many human inherited neurodegenerative disorders are characterized by loss of balance due to cerebellar Purkinje cell (PC) degeneration. Although the disease-causing mutations have been identified for a number of these disorders, the normal functions of the proteins involved remain, in many cases, unknown. To gain insight into the function of proteins involved in PC degeneration, we developed an interaction...

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PMID: 16713569
DOI: 10.1016/j.cell.2006.03.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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