Article
Recapitulation of the association of the Val66Met polymorphism of BDNF gene with BMI in Koreans.
Obesity (Silver Spring, Md.) - 1 Sept 2012
Hong Kyung-Won, Lim Ji-Eun, Go Min Jin, Shin Cho Yoon, Ahn Younjhin, Han Bok-Ghee, Oh Bermseok
Abstract excerpt
Recent evidence suggests that brain-derived neurotrophic factor (BDNF) regulates food intake and the control of body weight. A common polymorphism in human BDNF, Val66Met (single-nucleotide polymorphism database (dbSNP) no. rs6265), impairs intracellular trafficking, resulting in the reduced secretion of BDNF. Several European studies have indicated that Val66Met is associated with BMI. In this study, we examined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
