Article
G-protein beta3 subunit gene variant is unlikely to have a significant influence on serum uric acid level in Japanese workers.
The Tohoku journal of experimental medicine - 1 Jun 2006
Suwazono Yasushi, Kobayashi Etsuko, Uetani Mirei, Miura Katsuyuki, Morikawa Yuko, Ishizaki Masao, Kido Teruhiko, Nakagawa Hideaki, Nogawa Koji
Abstract excerpt
The C825T variant of the G-protein beta3 subunit (GNB3) gene has attracted renewed attention as a candidate gene for obesity, hypertension and hyperuricemia. The main role of G-protein is to translate signals from the cell surface into a cellular response. The 825T allele is associated with a splice variant of GNB3 protein and enhanced G-protein activation. We examined the relationship between this variant and...
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