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Article

Malignant Transformation of Immortalized HaCaT Keratinocytes through Deregulated Nuclear Factor κB Signaling

15 May 2006

Abstract excerpt

Previous studies addressing functional aspects of nuclear factor kappaB (NF-kappaB) activation in normal and transformed keratinocytes revealed complex and seemingly contradictory roles of this transcription factor in this cell type. In normal skin, NF-kappaB signaling seems to inhibit squamous cell carcinoma development whereas, in squamous cell carcinoma themselves, deregulated NF-kappaB expression and/or...

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PMID: 16707445
DOI: 10.1158/0008-5472.can-05-4158

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Malignant Transformation of Immortalized HaCaT Keratinocytes through Deregulated Nuclear Factor κB SignalingPMID 16707445Read ↗

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