Article
Genetic polymorphisms of platelet glycoprotein Ia and the risk for premature myocardial infarction: effects on the release of sCD40L during the acute phase of premature myocardial infarction.
Journal of the American College of Cardiology - 16 May 2006
Antoniades Charalambos, Tousoulis Dimitris, Vasiliadou Carmen, Stefanadi Elli, Marinou Kyriakoula, Stefanadis Christodoulos
Abstract excerpt
OBJECTIVES: The aim of this research was to evaluate the effect of genetic polymorphisms C807T and G1648A of platelet glycoprotein Ia (GPIa), on the risk for myocardial infarction (MI) and on the release of soluble CD40 ligand (sCD40L) during the acute phase of MI and one year after the event. BACKGROUND: C807T and G1648A polymorphisms affect the density of GPIa on platelet surface, but their effect on the risk...
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