Article
Myocardial infarction before and after the age of 45: Possible role of platelet receptor polymorphisms.
Revista portuguesa de cardiologia - 1 Sept 2018
Pina-Cabral Luís B, Carvalhais Virgínia, Mesquita Bárbara, Escórcio Cláudia, Silva Paulo F, Pinto Paula, Napoleão Patrícia, Pinheiro Teresa, Monteiro Maria C, Almeida-Dias António, Criado Begoña
Abstract excerpt
INTRODUCTION: We examined the potential role of polymorphisms of the platelet genes GP1BA (rs2243093, rs6065 and VNTR), ITGB3 (rs5918), ITGA2 (rs938043469) and P2RY12 (rs2046934, rs6801273 and ) as risk factors for myocardial infarction (MI). METHODS: The study population was divided into three groups: controls (n=235), MI at age ≤45 years (MI ≤45, n=44), and MI at age >45 years (MI >45, n=78). The...