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Article

NPT2a gene variation in calcium nephrolithiasis with renal phosphate leak.

Kidney international - 1 Jun 2006

Lapointe J-Y, Tessier J, Paquette Y, Wallendorff B, Coady M J, Pichette V, Bonnardeaux A

Abstract excerpt

A decrease in renal phosphate reabsorption with mild hypophosphatemia (phosphate leak) is found in some hypercalciuric stone-formers. The NPT2a gene encodes a sodium-phosphate cotransporter, located in the proximal tubule, responsible for reclaiming most of the filtered phosphate load in a rate-limiting manner. To determine whether genetic variation of the NPT2a gene is associated with phosphate leak and...

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Source

Identifiers

PMID: 16688119
DOI: 10.1038/sj.ki.5000437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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