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Article

Telomerase activity and hTERT mRNA expression in glial tumors

1 Jun 2006

Abstract excerpt

Human telomerase is a structurally complex ribonucleoprotein that is responsible for the maintenance of telomeric DNA at the ends of the chromosomes. The enzyme is proposed as having an important role in cell immortalization and oncogenesis. A limited number of studies have been performed on the telomerase system in brain tumors, and these studies are somewhat conflicting. The relative ineffectiveness of current...

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PMID: 16685456
DOI: 10.3892/ijo.28.6.1555

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