Article
Functional characterization of the flagellar glycosylation locus in Campylobacter jejuni 81-176 using a focused metabolomics approach.
The Journal of biological chemistry - 7 Jul 2006
McNally David J, Hui Joseph P M, Aubry Annie J, Mui Kenneth K K, Guerry Patricia, Brisson Jean-Robert, Logan Susan M, Soo Evelyn C
Abstract excerpt
Bacterial genome sequencing has provided a wealth of genetic data. However, the definitive functional characterization of hypothetical open reading frames and novel biosynthetic genes remains challenging. This is particularly true for genes involved in protein glycosylation because the isolation of their glycan moieties is often problematic. We have developed a focused metabolomics approach to define the function...
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