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Article

Double heterozygotes for non-Caucasian families with mutations in BRCA-1 and BRCA-2 genes.

The breast journal - 1 Jan 2000

Choi Doo Ho, Lee Min Hyuk, Haffty Bruce G

Abstract excerpt

The recent discovery of the BRCA-1 and BRCA-2 genes as contributing factors to hereditary breast cancer has significantly improved our understanding of familial breast cancer. Deleterious mutations in both BRCA-1 and BRCA-2 in an individual patient is exceedingly rare, with few case reports in the literature, particularly among non-Caucasian, non-Jewish families. We describe here two cases of deleterious...

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Identifiers

PMID: 16684319
DOI: 10.1111/j.1075-122X.2006.00245.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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