Article
Autopsy and postmortem examination case study on genetic risk factors for cardiac death: polymorphisms of endothelial nitric oxide synthase gene Glu298Asp variant and T-786C mutation, human paraoxonase 1 (PON1) gene and alpha2beta-adrenergic receptor gene.
Vojnosanitetski pregled - 1 Apr 2006
Ameno Kiyoshi, Ameno Setsuko, Kinoshita Hiroshi, Jamal Mostofa, Wang Weihuan, Kumihashi Mitsuru, Uekita Ikuo, Ijiri Iwao
Abstract excerpt
BACKGROUND/AIM: The Glu298Asp variant in exon 7 and T-786C mutation in the 5'-flanking region of the endothelial nitric oxide synthase (eNOS) gene, paraoxonase I gene (PON1), and alpha2beta-adrenergic receptor gene (alpha2beta-AR) have been reported to be genetic risk factors for coronary heart disease (CHD). The aim of this study was to investige the effects of these four genetic polymorphisms on the probability...
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