Article
Critical role of tryptophanyl residues in the conformational stability of goose delta-crystallin.
Experimental eye research - 1 Sept 2006
Lee Hwei-Jen, Lai Young-Hsang, Huang Yu-Ting, Huang Chih-Wei, Chen Yu-Hou, Chang Gu-Gang
Abstract excerpt
Delta-crystallin is the major structural protein in avian and reptilian eye lenses but its sequence is highly homologous with the urea cycle enzyme, argininosuccinate lyase (ASL). In previous studies the multi-step unfolding process of this protein in the presence of GdmCl was sensitively probed...
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