Article
Maintaining genetic integrity in aging: a zero sum game.
Antioxidants & redox signaling - 1 Jan 2000
Suh Yousin, Vijg Jan
Abstract excerpt
Aging of somatic cells can be defined as the gradual loss of the information embedded in the global and local properties of complex macromolecular networks. This loss of information may reflect the dynamic interplay between stochastic factors, such as the accumulation of unrepaired somatic damage, and gene-encoded programmatic responses. This would ultimately result in loss of function, impaired response to...
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