Article
Erythrocyte fructose 2,6-bisphosphate content in congenital hemolytic anemias.
Hemoglobin - 1 Jan 1991
Colomer D, Pujades A, Carballo E, Vives Corrons J L
Abstract excerpt
We have investigated the levels of fructose 2,6-bisphosphate and its synthesizing enzyme 6-phosphofructo-2-kinase in red blood cells from different congenital anemias. Fructose 2,6-bisphosphate concentration and 6-phosphofructo-2-kinase activity are markedly influenced by the number of reticulocytes in all the cases studied with the exception of homozygous pyruvate kinase deficiency, where no correlation was...
Topics
- Anemia, Hemolytic, Congenital
- Anemia, Sickle Cell
- Erythrocytes
- Fructosediphosphates
- Genotype
- Glucosephosphate Dehydrogenase
- Glucosephosphate Dehydrogenase Deficiency
- Glycolysis
- Hexokinase
- Humans
- Phosphofructokinase-2