Article
The identification and cloning of the murine genes encoding the liver specific F alloantigens.
Journal of autoimmunity - 1 Dec 1991
Teuber S S, Coppel R L, Ansari A A, Leung P S, Neve R, Mackay I R, Gershwin M E
Abstract excerpt
The liver specific F alloantigen is a highly conserved abundant protein found in hepatic cytoplasm; smaller amounts are detected in renal tubule cells and the perikaryon cells of the central nervous system. Although the biological function of the F alloantigen is unknown, the immune response to F has been extensively studied as a murine model of tolerance and autoimmunity. Murine F exists in two allelic forms,...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Western
- Cloning, Molecular
- DNA Probes
- Histocompatibility Antigens Class II
- Immunization
- Isoantigens
- Liver
- Mice
