Regulatory roles for mitochondria in the peri-implantation mouse blastocyst: possible origins and developmental significance of differential ΔΨm

Abstract excerpt

Studies of mitochondria in mouse and human oocytes and preimplantation stage embryos have focused primarily on their metabolic capacity to generate ATP. However, it is becoming increasingly apparent that mitochondria are also regulatory agents in other processes involved in the establishment of developmental competence, including calcium homeostasis and apoptosis. The magnitude of the inner mitochondrial membrane...

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