Article
Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster.
The Journal of cell biology - 8 May 2006
Wood Will, Faria Celia, Jacinto Antonio
Abstract excerpt
Drosophila melanogaster hemocytes are highly motile macrophage-like cells that undergo a stereotypic pattern of migration to populate the whole embryo by late embryogenesis. We demonstrate that the migratory patterns of hemocytes at the embryonic ventral midline are orchestrated by chemotactic signals from the PDGF/VEGF ligands Pvf2 and -3 and that these directed migrations occur independently of phosphoinositide...
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