Article
Chemokine Signaling and the Regulation of Bidirectional Leukocyte Migration in Interstitial Tissues.
Cell reports - 23 May 2017
Powell Davalyn, Tauzin Sebastien, Hind Laurel E, Deng Qing, Beebe David J, Huttenlocher Anna
Abstract excerpt
Motile cells navigate through complex tissue environments that include both attractive and repulsive cues. In response to tissue wounding, neutrophils, primary cells of the innate immune response, exhibit bidirectional migration that is orchestrated by chemokines and their receptors. Although progress has been made in identifying signals that mediate the recruitment phase, the mechanisms that regulate neutrophil...
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