X-linked premature ovarian failure: a complex disease.

doi:10.1016/j.gde.2006.04.005

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Article

X-linked premature ovarian failure: a complex disease.

Current opinion in genetics & development - 1 Jun 2006

Toniolo Daniela

Abstract excerpt

Involvement of the X chromosome in premature ovarian failure was demonstrated by the relatively frequent chromosomal rearrangements in patients, but the requirement of two X chromosomes for ovarian function was quite unexplained until recently. Review of the data on chromosomal rearrangements suggests that several genes along the X chromosomes contribute to ovarian function. In most instances, no single X...

Topics

Animals
Female
Genes, X-Linked
Humans
Monosomy
Mutation
Primary Ovarian Insufficiency
Turner Syndrome
X Chromosome

Source

Open in PubMed

Identifiers

PMID: 16650756
DOI: 10.1016/j.gde.2006.04.005

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