Article
X-linked premature ovarian failure: a complex disease.
Current opinion in genetics & development - 1 Jun 2006
Toniolo Daniela
Abstract excerpt
Involvement of the X chromosome in premature ovarian failure was demonstrated by the relatively frequent chromosomal rearrangements in patients, but the requirement of two X chromosomes for ovarian function was quite unexplained until recently. Review of the data on chromosomal rearrangements suggests that several genes along the X chromosomes contribute to ovarian function. In most instances, no single X...
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