Article
Splicing of retrotransposon insertions from transcripts of the Drosophila melanogaster vermilion gene in a revertant.
Genetics - 1 Dec 1991
Pret A M, Searles L L
Abstract excerpt
A mutation of the Drosophila melanogaster vermilion (v) gene known as v1 is caused by the insertion of a 412 retrotransposon into the 5' untranslated region of the first exon. Mutants carrying this insertion accumulate a low level of mRNA from which most of the transposon sequences have been eliminated by splicing at cryptic sites within transposon sequences. Here, we demonstrate that a revertant of the v1 allele...
Topics
- Animals
- Base Sequence
- Blotting, Northern
- DNA
- DNA Transposable Elements
- Drosophila melanogaster
- Introns
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- RNA Splicing