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Article

Association of NRAMP 1 gene polymorphism with susceptibility to tuberculosis in Taiwanese aboriginals.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 May 2006

Hsu Yung-Hsiang, Chen Chaio-Wei, Sun H Sunny, Jou Ruwen, Lee Jen-Jyh, Su Ih-Jen

Abstract excerpt

BACKGROUND/PURPOSE: The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a five-fold higher prevalence of tuberculosis than people of Han ethnicity. Whether genetic factors such as NRAMP 1 polymorphism play a role in the prevalence of tuberculosis...

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PMID: 16638645
DOI: 10.1016/S0929-6646(09)60131-5

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