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Article

The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1).

The Journal of general physiology - 1 May 2006

Marmorstein Lihua Y, Wu Jiang, McLaughlin Precious, Yocom John, Karl Mike O, Neussert Rudgar, Wimmers Soenke, Stanton J Brett, Gregg Ronald G, Strauss Olaf, Peachey Neal S, Marmorstein Alan D

Abstract excerpt

Mutations in VMD2, encoding bestrophin (best-1), cause Best vitelliform macular dystrophy (BMD), adult-onset vitelliform macular dystrophy (AVMD), and autosomal dominant vitreoretinochoroidopathy (ADVIRC). BMD is distinguished from AVMD by a diminished electrooculogram light peak (LP) in the abse...

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Identifiers

PMID: 16636205
DOI: 10.1085/jgp.200509473
PMCID: PMC2151522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16636205-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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