Article
Spurious hemoglobin Barts caused by bilirubin: a common interference mimicking an uncommon hemoglobinopathy.
American journal of clinical pathology - 1 Apr 2006
Howanitz Peter J, Kozarski Tzvetan B, Howanitz Joan H, Chauhan Yeshpal S
Abstract excerpt
High-performance liquid chromatography (HPLC) is replacing electrophoresis for identification of hemoglobin variants. Our objective was to identify unknown tall peaks with elution times and shapes of hemoglobin Barts found on hemoglobin chromatograms that could not be confirmed by alkaline and acid gel electrophoresis. Of 90 specimens identified with this peak, 86 were from patients with hemoglobin SS. Regression...
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