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Article

Abnormal beta-catenin and reduced axin expression are associated with poor differentiation and progression in non-small cell lung cancer.

American journal of clinical pathology - 1 Apr 2006

Xu Hong-Tao, Wang Liang, Lin Dong, Liu Yang, Liu Nan, Yuan Xi-Ming, Wang En-Hua

Abstract excerpt

We studied the expression of axin and beta-catenin and their relation to clinicopathologic factors in 100 non-small cell lung cancers (NSCLCs) by immunohistochemical analysis. The mutation in exon 3 of the beta-catenin gene was examined by polymerase chain reaction and direct sequencing. Preserved axin expression was significantly higher in well- and moderately differentiated NSCLC samples than in poorly...

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Identifiers

PMID: 16627264
DOI: 10.1309/0MDY-02KH-EW1F-6RT6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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