Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of an oculomotor biomarker of preclinical Huntington disease

20 Apr 2006

Abstract excerpt

The authors examined oculomotor function to identify a biomarker of disease progression in genetically confirmed preclinical and early clinical Huntington disease (HD). Initiation deficits of voluntary-guided, but not reflexive, saccades were characteristic of preclinical HD. Saccadic slowing and delayed reflexive saccades were demonstrated in clinical but not preclinical HD. Saccadic measures provide biomarkers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Neurodegenerative Diseases
Share to Neurological disorders and treatments
Share to Neuroscience and Neuropharmacology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16625001
DOI: 10.1212/01.wnl.0000218215.43328.88

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of an oculomotor biomarker of preclinical Huntington diseasePMID 16625001Read ↗

Saccades in presymptomatic and early stages of Huntington disease.Semantic proximity Read ↗

[Disorders in gaze saccades in Huntington disease. Clinical correlations].Semantic proximity Read ↗

Oculomotor deficits in spinocerebellar ataxia type 3: Potential biomarkers of preclinical detection and disease progression.Semantic proximity Read ↗

Quantitative Oculomotor Assessment in Hereditary Ataxia: Discriminatory Power, Correlation with Severity Measures, and Recommended Parameters for Specific Genotypes.Semantic proximity Read ↗

Ocular motor biomarkers in Niemann-Pick disease type C: A prospective cross-sectional multicontinental study in 72 patientsSemantic proximity Read ↗

The Clinical Features and Progression of Late-Onset Versus Younger-Onset in an Adult Cohort of Huntington's Disease Patients.Semantic proximity Read ↗

Evaluating motor progression of juvenile-onset Huntington's Disease: An Enroll-HD analysis.Semantic proximity Read ↗

Slowed vertical saccades as a hallmark of hereditary spastic paraplegia type 7Semantic proximity Read ↗

Multimodal oculomotor assessment reveals prodromal markers of Parkinson’s disease in non-manifesting LRRK2 G2019S mutation carriersSemantic proximity Read ↗

Motor disorder in Huntington's disease begins as a dysfunction in error feedback control.Semantic proximity Read ↗

Multiple step pattern as a biomarker in Parkinson disease.Semantic proximity Read ↗

Psychomotor, executive, and memory function in preclinical Huntington's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.