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Article

Augmented levels of CD44 in macrophages from atherosclerotic subjects: a possible IL-6-CD44 feedback loop?

Atherosclerosis - 1 Feb 2007

Hägg Daniel, Sjöberg Sara, Hultén Lillemor Mattsson, Fagerberg Björn, Wiklund Olov, Rosengren Annika, Carlsson Lena M S, Borén Jan, Svensson Per-Arne, Krettek Alexandra

Abstract excerpt

The cell-adhesion molecule CD44 likely participates in atherosclerosis development. We have shown previously that pro-inflammatory cytokines affect CD44 expression. Therefore, this work examined the role of elevated CD44 levels in human macrophages. Macrophages from human atherosclerotic subjects (n=15) showed elevated levels of CD44 transcript and protein (1.5-fold) compared to matched controls (n=15) (P=0.050...

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PMID: 16620830
DOI: 10.1016/j.atherosclerosis.2006.03.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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