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Article

Identification of cis-regulatory elements for MECP2 expression.

Human molecular genetics - 1 Jun 2006

Liu Jinglan, Francke Uta

Abstract excerpt

Rett syndrome (RTT) is an X-linked dominant disabling neurodevelopmental disorder caused by loss of function mutations in the MECP2 gene, located at Xq28, which encodes a multifunctional protein. MECP2 expression is regulated in a developmental stage and cell-type-specific manner. The need for tightly controlled MeCP2 levels in brain is strongly suggested by neurologically abnormal phenotypes of mouse models with...

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Source

Identifiers

PMID: 16613900
DOI: 10.1093/hmg/ddl099

Genes

MECP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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