Article
Obesity-related derangements of coagulation and fibrinolysis: a study of obesity-discordant monozygotic twin pairs.
Obesity (Silver Spring, Md.) - 1 Jan 2012
Kaye Sanna M, Pietiläinen Kirsi H, Kotronen Anna, Joutsi-Korhonen Lotta, Kaprio Jaakko, Yki-Järvinen Hannele, Silveira Angela, Hamsten Anders, Lassila Riitta, Rissanen Aila
Abstract excerpt
Coagulation and fibrinolytic activities are under strong genetic control. We studied the effects of acquired obesity, independent of genetic factors on coagulation and fibrinolysis activities in obesity-discordant healthy monozygotic (MZ) twin pairs. Fourteen obesity-discordant (BMI within-pair difference >3 kg/m(2)) and 10 concordant (BMI difference <2 kg/m(2)) MZ twin pairs were identified from the nationwide...
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