Article
[Effect of R264C polymorphism in CYP19A1 gene on BRCA1/2-negative hereditary breast cancer from Shanghai population of China].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2006
Song Chuan-gui, Hu Zhen, Yuan Wen-tao, Di Gen-hong, Shen Zhen-zhou, Huang Wei, Shao Zhi-min
Abstract excerpt
OBJECTIVE: Aromatase, encoded by CYP19A1, play an important role in estrogens biosynthesis from androgens. The present study is to investigate effect of R264C single nucleotide polymorphism in CYP19A1 gene on genetic susceptibility for hereditary breast cancer without BRCA1/2 mutant. METHODS: One...
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