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Article

9-Tetrahydrocannabinol inhibits cytotrophoblast cell proliferation and modulates gene transcription

6 Apr 2006

Abstract excerpt

Cannabis use in pregnancy is associated with a range of obstetrical conditions. The molecular mechanisms underlying these effects have not been elucidated but are attributed to the actions of delta-9-tetrahydrocannabinol (Delta9-THC). In this study, concentrations of Delta9-THC equivalent to those found in the serum of cannabis users, i.e. approximately 20 microM, inhibited proliferation and activated a...

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PMID: 16597638
DOI: 10.1093/molehr/gal036

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