Expression of the Endocannabinoid System in Human First Trimester Placenta and Its Role in Trophoblast Proliferation

Abstract excerpt

The endocannabinoid, anandamide, which binds to two major receptor proteins, the cannabinoid receptors (CBs) 1 and 2 (CB1 and CB2), has been shown to play a role in first trimester miscarriage possibly through impairment of the developing trophoblast. Although the precise molecular mechanisms underlying this are unknown, plasma anandamide levels are known to be regulated by the progesterone-induced enzyme, fatty...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Birth, Development, and Health
• Share to Cannabis and Cannabinoid Research
• Share to Prenatal Substance Exposure Effects