Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cannabidiol Disrupts Mitochondrial Respiration and Metabolism and Dysregulates Trophoblast Cell Differentiation

11 Mar 2024

Abstract excerpt

Trophoblast differentiation is a crucial process in the formation of the placenta where cytotrophoblasts (CTs) differentiate and fuse to form the syncytiotrophoblast (ST). The bioactive components of cannabis, such as Δ9-THC, are known to disrupt trophoblast differentiation and fusion, as well as mitochondrial dynamics and respiration. However, less is known about the impact of cannabidiol (CBD) on trophoblast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cannabis and Cannabinoid Research
Share to Diet, Metabolism, and Disease
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38534330
DOI: 10.3390/cells13060486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cannabidiol Disrupts Mitochondrial Respiration and Metabolism and Dysregulates Trophoblast Cell DifferentiationPMID 38534330Read ↗

Delta-9-tetrahydrocannabinol inhibits invasion of HTR8/SVneo human extravillous trophoblast cells and negatively impacts mitochondrial functionSemantic proximity Read ↗

Cannabis Smoke Extract Disrupts Trophoblast Differentiation and Causes Mitochondrial Dysfunction Beyond the Effects Of Δ9-THC AloneSemantic proximity Read ↗

Trophoblast syncytialisation necessitates mitochondrial function through estrogen-related receptor- activationSemantic proximity Read ↗

Δ9-Tetrahydrocannabinol leads to endoplasmic reticulum stress and mitochondrial dysfunction in human BeWo trophoblastsSemantic proximity Read ↗

Proteomic Analysis of Placental Mitochondria Following Trophoblast DifferentiationSemantic proximity Read ↗

Mitochondrial dynamics, biogenesis, mitophagy and oxidative stress in gestational obesity: A reviewSemantic proximity Read ↗

Placental mitochondria and reactive oxygen species in the physiology and pathophysiology of pregnancySemantic proximity Read ↗

Dichotomy in hypoxia-induced mitochondrial fission in placental mesenchymal cells during development and preeclampsia: consequences for trophoblast mitochondrial homeostasisSemantic proximity Read ↗

Benzo(a)pyren-7,8-dihydrodiol-9,10-epoxide induces human trophoblast Swan 71 cell dysfunctions due to cell apoptosis through disorder of mitochondrial fission/fusionSemantic proximity Read ↗

Placental Mitochondrial Abnormalities in PreeclampsiaSemantic proximity Read ↗

Bisphenol S moderately decreases the expression of syncytiotrophoblast marker genes and induces apoptosis in human trophoblast lineagesSemantic proximity Read ↗

9-Tetrahydrocannabinol inhibits cytotrophoblast cell proliferation and modulates gene transcriptionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.