Article
Genetically determined apo B levels and peak LDL density predict angiographic response to intensive lipid-lowering therapy.
Journal of internal medicine - 1 Apr 2006
Zambon A, Brown B G, Hokanson J E, Motulsky A G, Brunzell J D
Abstract excerpt
OBJECTIVE: Lipid-lowering therapy (LL-Rx) reduces coronary artery disease (CAD) but the response varies amongst individuals. We investigated the contribution of three genetic forms of dyslipidaemia characterized by elevated plasma apo B, familial hypercholesterolaemia (FH), familial combined hyperlipidaemia (FCHL), and elevated Lp(a), to the angiographic response with LL-Rx. METHODS AND RESULTS: Fifty-one men,...
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