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Article

Genetic selection of a flavivirus-refractory strain of the yellow fever mosquito Aedes aegypti.

The American journal of tropical medicine and hygiene - 1 Oct 1991

Miller B R, Mitchell C J

Abstract excerpt

Two inbred (isofemale) Aedes aegypti mosquito lines were derived that manifested a resistant or susceptible phenotype following ingestion of yellow fever virus; lack of virus movement from the midgut defined the resistant phenotype. Other flaviviruses, including dengue 1-4, Uganda S, and Zika, viruses behaved in a similar fashion in the two mosquito lines. Crosses between the two lines produced progeny that were...

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PMID: 1659238
DOI: 10.4269/ajtmh.1991.45.399

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