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Article

Genetic selection of a flavivirus-refractory strain of the yellow fever mosquito Aedes aegypti.

The American journal of tropical medicine and hygiene - 1 Oct 1991

Miller B R, Mitchell C J

Abstract excerpt

Two inbred (isofemale) Aedes aegypti mosquito lines were derived that manifested a resistant or susceptible phenotype following ingestion of yellow fever virus; lack of virus movement from the midgut defined the resistant phenotype. Other flaviviruses, including dengue 1-4, Uganda S, and Zika, viruses behaved in a similar fashion in the two mosquito lines. Crosses between the two lines produced progeny that were...

Topics

Aedes
Animals
Dengue Virus
Female
Flavivirus
Humans
Inbreeding
Insect Vectors
Macaca mulatta
Nigeria
Phenotype
Yellow fever virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Zika Virus

Source

Identifiers

PMID: 1659238
DOI: 10.4269/ajtmh.1991.45.399

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1659238-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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