Article
Antigenic shift and increased incidence of meningococcal disease.
The Journal of infectious diseases - 1 May 2006
Harrison Lee H, Jolley Keith A, Shutt Kathleen A, Marsh Jane W, O'Leary Mary, Sanza Laurie Thomson, Maiden Martin C J
Abstract excerpt
BACKGROUND: The incidence of serogroup C and Y meningococcal disease increased in the United States during the 1990s. The cyclical nature of endemic meningococcal disease remains unexplained. The purpose of this study was to investigate the mechanisms associated with the increase in the incidence of meningococcal disease. METHODS: We characterized an increasing incidence of invasive serogroup C and Y...
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