Article
Molecular evidence for mother-to-child transmission of Kaposi sarcoma-associated herpesvirus in Uganda and K1 gene evolution within the host.
The Journal of infectious diseases - 1 May 2006
Mbulaiteye Sam, Marshall Vickie, Bagni Rachel K, Wang Cheng-Dian, Mbisa Georgina, Bakaki Paul M, Owor Anchilla M, Ndugwa Christopher M, Engels Eric A, Katongole-Mbidde Edward, Biggar Robert J, Whitby Denise
Abstract excerpt
BACKGROUND: Epidemiological studies of Kaposi sarcoma (KS)-related herpesvirus (KSHV) indicate that having a KSHV-seropositive mother is a risk factor for KSHV infection in children. METHODS: We determined the KSHV K1 sequences in concordantly polymerase chain reaction-positive Ugandan mother-child pairs, to ascertain whether they shared the same viral strain. We also examined sequences amplified from saliva and...
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