Article
Proliferating cell nuclear antigen (PCNA) expression in pituitary adenomas: relationship to the endocrine phenotype of adenoma.
Folia histochemica et cytobiologica - 1 Jan 2006
Pawlikowski Marek, Gruszka Anna, Kurnatowska Ilona, Winczyk Katarzyna, Kunert-Radek Jolanta, Radek Andrzej
Abstract excerpt
The expression of proliferating cell nuclear antigen (PCNA) correlates to cell proliferation and for this reason it is commonly considered as one of proliferation markers. Since proliferation rate is an important factor determining the tumor aggressiveness, the evaluation of PCNA index (the percentage of PCNA-immunopositive nuclei in the investigated tumor sample) is suggested as useful in predicting pituitary...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
