Article
[Management of gynecological tumors associated with BRCA1 and BRCA2 germline mutations. Case report and literature review].
Minerva ginecologica - 1 Apr 2006
Fruscalzo A, Lellé R J, Calcagno A, Driul L, Damante G, Marchesoni D
Abstract excerpt
Genetic investigation of BRCA1 and BRCA2 germline mutations is, nowadays, a diagnostic procedure with practical clinical applications. The role of this genes in DNA repair and stability and in cancer development is now well recognised. Most involved are breast and ovarian cancers, but, less frequently, other gynecological cancers like cervical, corpus uteri and Fallopian tubes cancers and also other non...
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