Article
Expression of HLA class I heavy chains and beta 2-microglobulin does not affect human cytomegalovirus infectivity.
The Journal of general virology - 1 Nov 1991
Beersma M F, Wertheim-van Dillen P M, Geelen J L, Feltkamp T E
Abstract excerpt
Human cytomegalovirus (HCMV) purified from urine or tissue culture supernatant has been reported to contain beta 2-microglobulin (beta 2m), which forms the light chain of HLA class I molecules. It has been postulated that HCMV covered with beta 2m binds to HLA class I alpha-chains at the cell sur...
Topics
- Alleles
- Animals
- Antibodies, Monoclonal
- Cytomegalovirus
- Fluorescence
- HLA Antigens
- Histocompatibility Antigens Class I
- Humans
- L Cells
- Mice
- Receptors, Virus
- Transfection
- Trypsin
- Tumor Cells, Cultured
- Virus Replication
- beta 2-Microglobulin