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Article

Molecular biology of oral cavity squamous cell carcinoma.

Otolaryngologic clinics of North America - 1 Apr 2006

Kupferman Michael E, Myers Jeffrey N

Abstract excerpt

Significant advances have been made in understanding the mechanisms that contribute to carcinogenesis in OCSCC. This progress has led to the development of therapeutic strategies that target dysregulated processes in the tumor microenvironment (Fig. 11) [72]. The introduction of angiogenesis inhibitors, growth factor receptor tyrosine kinase inhibitors, and cell cycle regulators into clinical trials for the...

Topics

Carcinoma, Squamous Cell
Cell Cycle
Cell Transformation, Neoplastic
DNA, Neoplasm
Genes, Tumor Suppressor
Humans
Molecular Biology
Mouth Neoplasms
Mutation
Neoplasm Invasiveness
Neoplasm Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neovascularization, Pathologic

Oncogenes

Source

Identifiers

PMID: 16580909
DOI: 10.1016/j.otc.2005.11.003

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