Article
Detection of human papillomavirus DNA, p53 and ki67 expression in penile carcinomas.
International journal of immunopathology and pharmacology - 1 Jan 2000
Gentile V, Vicini P, Giacomelli L, Cardillo M R, Pierangeli A, Degener A M
Abstract excerpt
Our study is aimed at evaluating the presence of p53 and Ki67 expression by immunohistochemistry in a series of 11 paraffin-embedded penile carcinomas. We also investigated the presence of Human Papillomavirus (HPV) DNA in these tumours and performed an accurate typing by DNA sequencing on positive samples. Immunohistochemistry (IHC) was performed with the anti-p53 and Ki67 mouse monoclonal antibodies. DNA...
Topics
- DNA, Viral
- Genotype
- Humans
- Immunohistochemistry
- Ki-67 Antigen
- Lymph Node Excision
- Male
- Papillomaviridae
- Paraffin Embedding
- Penile Neoplasms
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Suppressor Protein p53
