Article
CD38 as a prognostic factor in B cell chronic lymphocytic leukaemia (B-CLL): comparison of three approaches to analyze its expression.
Cytometry. Part B, Clinical cytometry - 1 May 2006
Boonstra Joke G, van Lom Kirsten, Langerak Anton W, Graveland Wilfried J, Valk Peter J M, Kraan Jaco, van 't Veer Mars B, Gratama Jan W
Abstract excerpt
BACKGROUND: Increased CD38 expression by leukemic cells has been suggested as an adverse prognostic factor in B-CLL. Several approaches have been proposed to quantify its level of expression by flow cytometry. METHODS: We compared the use of (i) the percentage of CD38 positive cells, (ii) CD38 antibodies bound per cell (ABC), and (iii) a semi-quantitative method based on the shape of the CD38 histogram, within a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.