Article
The inherited genetics of pancreatic cancer and prospects for secondary screening.
Best practice & research. Clinical gastroenterology - 1 Apr 2006
Vitone Louis J, Greenhalf William, McFaul Christopher D, Ghaneh Paula, Neoptolemos John P
Abstract excerpt
It is estimated that pancreatic cancer has a familial component in approximately 5-10% of cases. Some of these cases are part of a defined cancer syndrome with a known gene mutation but in the remaining the causative gene remains unknown. In recent years, a better understanding of the molecular events that occur in the progression model of pancreatic cancer has lead to the development of secondary screening...
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