Article
Parvalbumin and calbindin D-28k immunoreactivity in transgenic mice with a G93A mutant SOD1 gene.
Brain research - 14 Apr 2006
Sasaki Shoichi, Warita Hitoshi, Komori Takashi, Murakami Tetsuro, Abe Koji, Iwata Makoto
Abstract excerpt
Immunohistochemical study was performed to examine if calcium-binding proteins are involved in the degeneration of motor neurons in the brain stems and the spinal cords of transgenic mice carrying a G93A mutant human SOD1 gene. Specimens from age-matched non-transgenic wild-type mice served as controls. In the spinal cord of the controls, the density of parvalbumin-immunoreactive neurons was highest in the large...
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