Article
The first round of mouse spermatogenesis is a distinctive program that lacks the self-renewing spermatogonia stage
15 Mar 2006
Abstract excerpt
Mammalian spermatogenesis is maintained by a continuous supply of differentiating cells from self-renewing stem cells. The stem cell activity resides in a small subset of primitive germ cells, the undifferentiated spermatogonia. However, the relationship between the establishment of this population and the initiation of differentiation in the developing testes remains unclear. In this study, we have investigated...
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