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Article

Pregnancy-associated plasma protein-A polymorphism and the risk of recurrent pregnancy loss.

Journal of reproductive immunology - 1 Jun 2006

Suzuki Kana, Sata Fumihiro, Yamada Hideto, Saijo Yasuaki, Tsuruga Noriko, Minakami Hisanori, Kishi Reiko

Abstract excerpt

Pregnancy-associated plasma protein-A (PAPP-A)/insulin-like growth factor-binding protein-4 (IGFBP4) protease is a member of the metzincin family of metalloproteases, known as a sensitive biomarker of adverse pregnancy outcomes. Recently, a missense A/C (Tyr/Ser) polymorphism (dbSNP: rs7020782) in the PAPPA gene has been reported. To examine the association between recurrent pregnancy loss (RPL) and this...

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Source

Identifiers

PMID: 16540175
DOI: 10.1016/j.jri.2005.11.004

Genes

PAPPA
IGFBP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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