Article
Studies on the human leukocyte antigens in patients with polycystic ovary syndrome in a Japanese population--possible susceptibility of HLA-A11 and -DRB1*0403 to patient population with polycystic ovary syndrome.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Apr 2006
Kaibe Mamiko, Takakuwa Koichi, Murakawa Haruo, Ishii Keisuke, Tamura Masaki, Tanaka Kenichi
Abstract excerpt
PROBLEM: The objective of this study was to identify the human leukocyte antigen (HLA) alleles that confer susceptibility or resistance to polycystic ovary syndrome (PCOS) in the Japanese population. METHOD OF STUDY: HLA-A, -B and -C antigens were determined in 56 patients with PCOS using conventional serological method. HLA-DRB1 genotypes were determined using a polymerase chain reaction-restriction fragment...
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