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Article

Highly sensitive detection of HPV‐DNA in paraffin sections of human oral carcinomas

20 Dec 2006

Abstract excerpt

BACKGROUND: Although human papillomavirus (HPV) infection has been shown to be a significant carcinogen in cervical squamous cell carcinoma (SCC), its significance in oral SCC remains unclear. METHODS: We developed highly sensitive detection methods for HPV to elucidate the prevalence and localization of HPV in paraffin sections from human oral SCC using modified in situ polymerase chain reaction (PCR) and in...

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PMID: 17181737
DOI: 10.1111/j.1600-0714.2006.00490.x

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